研究人员
饶佳
发布时间:2019-03-25        浏览次数:891

饶佳


 

 

 


       复旦大学附属儿科医院,副主任医师,硕士生导师。入选2018年“国家自然科学基金-优秀青年科学基金”项目资助。在长期的临床和科研工作中,致力于探索小儿遗传性性肾脏疾病的机制研究,聚焦神经系统发育缺陷合并肾脏发育障碍及功能损害的综合征型疾病的突变谱系及分子机制。多篇研究发表于Nature Genetics、Journal of Clinical Investigation 等学术专刊。曾获上海市科技进步一等奖(第四完成人)。

教育研究经历
2014/09 - 2016/09 美国哈佛医学院,波士顿儿童医院,博士后
2010/09 - 2010/05 悉尼儿童医院,Clinical fellow
2001/09 - 2006/06 复旦大学附属儿科医院 儿科学,博士
1996/09 - 2001/06 复旦大学上海医学院 临床医学专业,学士

研究方向

儿童遗传性肾脏疾病

代表性论文

  1. Ashraf S, Kudo H, Rao J, Kikuchi A, Widmeier E, Lawson JA, Tan W, Hermle T, Warejko JK, Shril S, Airik M, Jobst-Schwan T, Lovric S, Braun DA, Gee HY, Schapiro D, Majmundar AJ, Sadowski CE, Pabst WL, Daga A, van der Ven AT, Schmidt JM, Low BC, Gupta AB, Tripathi BK, Wong J, Campbell K, Metcalfe K, Schanze D, Niihori T, Kaito H, Nozu K, Tsukaguchi H, Tanaka R, Hamahira K, Kobayashi Y, Takizawa T, Funayama R, Nakayama K, Aoki Y, Kumagai N, Iijima K, Fehrenbach H, Kari JA, El Desoky S, Jalalah S, Bogdanovic R, Stajić N, Zappel H, Rakhmetova A,  Wassmer SR, Jungraithmayr T, Strehlau J, Kumar AS, Bagga A, Soliman NA, Mane SM, Kaufman L, Lowy DR, Jairajpuri MA, Lifton RP, Pei Y, Zenker M, Kure S, Hildebrandt F(2018). Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. Nat Commun. 17;9(1):1960

  2. Rao J*, Ashraf S*, Tan W, van der Ven AT, Gee HY, Braun DA, Fehér K, George SP, Esmaeilniakooshkghazi A, Choi WI, Jobst-Schwan T, Schneider R, Schmidt JM, Widmeier E, Warejko JK, Hermle T, Schapiro D, Lovric S, Shril S, Daga A, Nayir A, Shenoy M, Tse Y, Bald M, Helmchen U, Mir S, Berdeli A, Kari JA, El Desoky S, Soliman NA, Bagga A, Mane S, Jairajpuri MA, Lifton RP, Khurana S, Martins JC, Hildebrandt F (2017). Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant  nephrotic syndrome. J Clin Invest. 127(12):4257-4269.

  3. Braun DA*, Rao J*, Mollet G, Schapiro D, Daugeron MC, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, Schmidt JM, Lawson JA, Schanze D, Ashraf S, Ullmann JFP, Hoogstraten CA, Boddaert N, Collinet B, Martin G, Liger D, Lovric S, Furlano M, Guerrera IC, Sanchez-Ferras O, Hu JF, Boschat AC, Sanquer S, Menten B, Vergult S, De Rocker N, Airik M, Hermle T, Shril S, Widmeier E, Gee HY, Choi WI, Sadowski CE, Pabst WL, Warejko JK, Daga A, Basta T, Matejas V, Scharmann K, Kienast SD, Behnam B, Beeson B, Begtrup A, Bruce M, Ch'ng GS, Lin SP, Chang JH, Chen CH, Cho MT, Gaffney PM, Gipson PE, Hsu CH, Kari JA, Ke YY, Kiraly-Borri C, Lai WM, Lemyre E, Littlejohn RO, Masri A, Moghtaderi M, Nakamura K, Ozaltin F, Praet M, Prasad C, Prytula A, Roeder ER, Rump P, Schnur RE, Shiihara T, Sinha MD, Soliman NA, Soulami K, Sweetser DA, Tsai WH, Tsai JD, Topaloglu R, Vester U, Viskochil DH, Vatanavicharn N, Waxler JL, Wierenga KJ, Wolf MTF, Wong SN, Leidel SA, Truglio G, Dedon PC, Poduri A, Mane S, Lifton RP, Bouchard M, Kannu P, Chitayat D, Magen D, Callewaert B, van Tilbeurgh H, Zenker M, Antignac C, Hildebrandt F(2017). Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Nat. Genet.;49(10):1529-1538

  4. Lin Y, Rao J# Zha XL, Xu H#(2013). Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin α(V)β3/FAK/PI3K pathway-mediated Rac1 activation. Biomed Res Int.;2013:135608

  5. Rao J, Kennedy SE, Cohen S, Rosenberg AR(2012). A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography. Acta Paediatr.; 101(3):224-229

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