研究员
联系方式
地址：上海市杨浦区淞沪路2005号复旦大学江湾校区生命科学学院D213室
电话：86 – 21 – 51630756 （office） 86-13917771279 （cell）
Email: lxue@fudan.edu.cn
研究方向
中枢神经系统突触传递机制研究，着重于突触传递的动力学调控，可塑性，分子细胞机制以及相关计算机建模。
教育及研究经历
复旦大学，2012年至今，研究员
美国国立卫生研究院，2010年至2012年，研究学者
美国国立卫生研究院，2005年至2010年，博士后
复旦大学，2000年至2005年，神经生物学，硕博连读研究生
复旦大学，1996年至2000年，遗传学，本科生
代表论文(*, 并列一作co-first; #, 通讯作者corresponding)
Guo J*, Ge JL*, Hao M*, Sun ZC*, Wu XS, Zhu JB, Wang W, Yao PT, Lin W and Xue L#. A Three-Pool Model Dissecting Readily Releasable Pool Replenishment at the Calyx of Held. (2015). Scientific Reports, 5:9517.
Guo J, Sun ZC, Yao PT, Wang HL and Xue L#. A Monte Carlo simulation dissecting quantal release at the calyx of Held. (2015). Front Biosci (Landmark Ed) 20:1079–1091.
Xue L*#, Sheng J*, Wu XS, Wu W, Luo FJ, Shin Wonchul, Chiang HC, and Wu LG#. (2013). Most vesicles in a central nerve terminal participate in recycling. Journal of Neuroscience，2013 May 15;33(20):8820-6.
Xu J, Luo F, Zhang Z, Xue L, Wu XS, Chiang HC, Shin W and Wu LG.(2013). SNARE Proteins Synaptobrevin, SNAP-25, and Syntaxin Are Involved in Rapid and Slow Endocytosis at Synapses. Cell reports, 02 May 2013, doi:10.1016/j.celrep.2013.03.010
Xue L#, Zhang Z#, McNeil B, Luo FJ, Wu XS, Sheng JS and Wu LG. (2012). Voltage-dependent calcium channels at the plasma membrane, but not vesicular channels, couple exocytosis to endocytosis. Cell reports, 1 (6) : 632-638.
Sheng JS，He L, Zheng H, Xue L, Luo FJ, Shin W, Sun T and Wu LG. (2012). Calcium-channel number critically influences synaptic strength and plasticity at the active zone. Nature Neuroscience, 15(7), 998–1006.
Xue L, McNeil BD, Wu XS, Luo FJ, He L and Wu LG. (2012). A Membrane Pool Retrieved via Endocytosis Overshoot at Nerve Terminals: A Study of Its Retrieval Mechanism and Role. Journal of Neuroscience, 2012 Mar 7; 2(10):3398-404.
Xue L and Mei YA. (2011). Synaptic vesicle cycling at the calyx of the Held. Acta Pharmacological Sinica, 2011 Mar;32(3):280-7.
Xue L and Wu LG. (2010). Post-tetanic potentiation is caused by two signaling mechanisms affecting quantal size and quantal content. Journal of Physiology (Lond.) 4987–4994.
He L#, Xue L#, Xu J, McNeil B, Bai L, Melicoff E, Adachi R and Wu LG. (2009) Compound vesicle fusion increases quantal size and potentiates synaptic transmission, Nature, 459(7243):93-7.
Xue L#, Zhang F, Chen X, Lin J, Shi J. PDZ Protein Mediated Activity-Dependent LTP/LTD Developmental Switch at Rat Retinocollicular Synapses. (2010). American Journal of Physiology, Cell Physiology, 298(6):C1572-82.