研究人员
薛磊
发布时间:2019-03-25        浏览次数:421

研究员


联系方式
地址:上海市杨浦区淞沪路2005号复旦大学江湾校区生命科学学院D213室
电话:86 – 21 – 51630756 (office)   86-13917771279 (cell)
Email: lxue@fudan.edu.cn

 


研究方向
中枢神经系统突触传递机制研究,着重于突触传递的动力学调控,可塑性,分子细胞机制以及相关计算机建模。

教育及研究经历 

  1. 复旦大学,2012年至今,研究员

  2. 美国国立卫生研究院,2010年至2012年,研究学者

  3. 美国国立卫生研究院,2005年至2010年,博士后

  4. 复旦大学,2000年至2005年,神经生物学,硕博连读研究生

  5. 复旦大学,1996年至2000年,遗传学,本科生

代表论文(*, 并列一作co-first;  #, 通讯作者corresponding)

  1. Guo J*, Ge JL*, Hao M*, Sun ZC*, Wu XS, Zhu JB, Wang W, Yao PT, Lin W and Xue L#. A Three-Pool Model Dissecting Readily Releasable Pool Replenishment at the Calyx of Held. (2015). Scientific Reports, 5:9517.

  2. Guo J, Sun ZC, Yao PT, Wang HL and Xue L#. A Monte Carlo simulation dissecting quantal release at the calyx of Held. (2015). Front Biosci (Landmark Ed) 20:1079–1091.

  3. Xue L*#, Sheng J*, Wu XS, Wu W, Luo FJ, Shin Wonchul, Chiang HC, and Wu LG#. (2013). Most vesicles in a central nerve terminal participate in recycling. Journal of Neuroscience,2013 May 15;33(20):8820-6.

  4. Xu J, Luo F, Zhang Z, Xue L, Wu XS, Chiang HC, Shin W and Wu LG.(2013). SNARE Proteins Synaptobrevin, SNAP-25, and Syntaxin Are Involved in Rapid and Slow Endocytosis at Synapses. Cell reports, 02 May 2013, doi:10.1016/j.celrep.2013.03.010

  5. Xue L#, Zhang Z#, McNeil B, Luo FJ, Wu XS, Sheng JS and Wu LG. (2012). Voltage-dependent calcium channels at the plasma membrane, but not vesicular channels, couple exocytosis to endocytosis. Cell reports, 1 (6) : 632-638.

  6. Sheng JS,He L, Zheng H, Xue L, Luo FJ, Shin W, Sun T and Wu LG. (2012). Calcium-channel number critically influences synaptic strength and plasticity at the active zone. Nature Neuroscience, 15(7), 998–1006.

  7. Xue L, McNeil BD, Wu XS, Luo FJ, He L and Wu LG. (2012). A Membrane Pool Retrieved via Endocytosis Overshoot at Nerve Terminals: A Study of Its Retrieval Mechanism and Role. Journal of Neuroscience, 2012 Mar 7; 2(10):3398-404.

  8. Xue L and Mei YA. (2011). Synaptic vesicle cycling at the calyx of the Held.  Acta Pharmacological Sinica, 2011 Mar;32(3):280-7.

  9. Xue L and Wu LG. (2010). Post-tetanic potentiation is caused by two signaling mechanisms affecting quantal size and quantal content. Journal of Physiology (Lond.)  4987–4994.

  10. He L#, Xue L#, Xu J, McNeil B, Bai L, Melicoff E, Adachi R and Wu LG. (2009) Compound vesicle fusion increases quantal size and potentiates synaptic transmission, Nature, 459(7243):93-7.

  11. Xue L#, Zhang F, Chen X, Lin J, Shi J. PDZ Protein Mediated Activity-Dependent LTP/LTD Developmental Switch at Rat Retinocollicular Synapses. (2010). American Journal of Physiology, Cell Physiology, 298(6):C1572-82.


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